Serotonin is a modern wellness center that combines mental health counseling, wellness programs, and self-care services to support overall mental and physical well-being.
KEY FRANCHISE STATS
Franchisees
?
2
+
n.a.
n.a.
Franchise fee
?
$59,000
Investment
?
$666,000 - $1,363,000
Revenue (AUV)
?
Undisclosed
$2,067,000
+
n.a.
n.a.
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Serotonin Centers is a forward-thinking health and wellness franchise focused on anti-aging, hormone optimization, weight management, immunity support, and aesthetic services. It was founded in 2021 by Eric Casaburi, the entrepreneur behind Retro Fitness.
The first location opened in Windermere, Florida, where the company is still headquartered. Serotonin began franchising the same year, branding itself as the nation's first human longevity franchise.
The franchise provides a comprehensive range of medically supervised services aimed at enhancing vitality and healthspan. Offerings include hormone replacement therapy, medical weight loss, IV therapy, red light therapy, and aesthetic treatments such as Botox and Hydrafacial.
Serotonin Centers also sell their own line of nutraceuticals, skincare products, and wellness apparel, offering multiple income streams for franchisees. What differentiates Serotonin Centers is its integrated approach that combines clinical oversight with personalized wellness coaching.
Initial investment
The initial investment required for a Serotonin franchise is
$666,000 - $1,363,000.
That is the total cost you would need to finance if you were to start this franchise.
These costs are provided by the franchisor in the Franchise Disclosure Document.
Type of Expenditure
Amount
Initial Franchise Fee
$59,000
Leasehold Improvements
$150,000 - $550,000
Furniture, Fixtures and Equipment
$50,000 - $61,000
Rent (3 months)
$15,000 - $48,000
Security Deposit
$5,000 - $16,000
Signage
$25,000 - $38,000
Services Equipment
$195,400 - $305,400
Startup Supplies
$63,694 - $71,694
Insurance Deposits and Premiums (3 months)
$3,750
Business Licenses and Permits
$5,000 - $11,000
Professional Fees
$8,000 - $25,000
Training Expenses
$2,000 - $4,500
Lease Review Fee
$1,800
Call Center Service Fee (2 months)
$1,990
Back Office Service Fee (1 month)
$0 - $995
Grand Opening Marketing
$10,000
Computers and Electronics
$20,000 - $25,100
Additional Funds for 3 months
$50,000 - $130,000
Total Estimated Initial Investment
$665,634 - $1,363,229
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Type of Expenditure
Amount
Initial Franchise Fee
$59,000
Leasehold Improvements
$150,000 - $550,000
Furniture, Fixtures and Equipment
$50,000 - $61,000
Rent (3 months)
$15,000 - $48,000
Security Deposit
$5,000 - $16,000
Signage
$25,000 - $38,000
Services Equipment
$195,400 - $305,400
Startup Supplies
$63,694 - $71,694
Insurance Deposits and Premiums (3 months)
$3,750
Business Licenses and Permits
$5,000 - $11,000
Professional Fees
$8,000 - $25,000
Training Expenses
$2,000 - $4,500
Lease Review Fee
$1,800
Call Center Service Fee (2 months)
$1,990
Back Office Service Fee (1 month)
$0 - $995
Grand Opening Marketing
$10,000
Computers and Electronics
$20,000 - $25,100
Additional Funds for 3 months
$50,000 - $130,000
Total Estimated Initial Investment
$665,634 - $1,363,229
Franchise Disclosure Document
Below is Serotonin's 2024 Franchise Disclosure Document. Upgrade to Pro or purchase the FDD to view and download the document.
Number of units
Serotonin had 4 total units in 2024, of which 2 were franchised-owned and 2 company-owned.
Serotonin offers a structured and mandatory training program to ensure franchisees and their staff are fully prepared to operate within the franchise system. The training programs offered by the franchisor include the following:
Initial Training Program: This must be completed by the franchisee (or Operating Principal) and the designated Manager before opening the franchise. The program is offered at Serotonin's headquarters, another specified location, or virtually, and is held at least quarterly. It includes instruction in general operations and clinical services, and is mandatory for operating the business.
Clinical Protocols Training: Authorized Care Providers are required to complete third-party vendor training on administering Proprietary Services such as hormone and IV therapies. Completion of this training to Serotonin’s satisfaction is required before these services can be provided.
Replacement and Additional Staff Training: If any trained staff leave the business, their replacements must complete the necessary management and clinical training within 30 days. Additional training is charged at $500 per person per day, plus expenses.
Territory Protection
Serotonin grants its franchisees a defined “Approved Territory,” typically determined as a three-mile drivable radius from the approved franchise location. Within this territory, and provided the franchisee complies with the agreement terms, Serotonin agrees not to establish or authorize another franchised business.
This territory is formalized in Schedule 1 of the franchise agreement, and franchisees must refrain from soliciting business outside of it without written permission. However, the protection has significant limitations.
Serotonin retains broad rights to conduct various business operations inside and outside the Approved Territory, including selling products online, through mail order, or at non-traditional venues like trade shows or “pop-up” locations.
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