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Medicine Shoppe

Home
Healthcare
Pharmacy

Medicine Shoppe

Medicine Shoppe Franchise FDD, Costs & Fees (2025)

Medicine Shoppe is a pharmacy franchise offering personalized pharmaceutical services, ensuring patients receive expert guidance and care for their medication needs.

Medicine Shoppe has empowered pharmacists to own and operate community-focused pharmacies. It was founded in 1970 in St. Louis, Missouri, and began franchising in 1971.

The company is still headquartered in St. Louis and operates under Medicine Shoppe International, a Cardinal Health company.

Medicine Shoppe franchise gives independent pharmacists the tools to deliver personalized care.

Franchisees offer prescription medications, over-the-counter health products, vitamins, wellness support, immunizations, and point-of-care testing. The franchise aims to restore the classic neighborhood pharmacy feel with modern efficiency.

Initial investment

Here's what you would need to invest if you were to start this franchise. These costs are provided by the franchisor in the Franchise Disclosure Document.

Type of Expenditure Amount
Initial Fee $0
Furniture, Fixtures & Equipment $42,000 - $95,000
Pre-Opening Costs $3,000 - $10,000
Leasehold Improvements $55,000 - $175,000
Signs & Installation $15,000 - $35,000
Opening Inventory $95,000 - $170,000
Grand Opening and Marketing $4,000 - $34,000
Accounts Receivable Financing $60,000 - $100,000
Computer and Pharmacy Equipment $26,000 - $40,000
Retail Solutions $0 - $14,075
Telepharmacy $0 - $35,865
Accreditation Costs $3,050 - $7,500
Additional Funds – 3 months $175,000 - $245,000
TOTAL $478,050 - $961,440
Type of Expenditure Amount
Initial Fee $0
Furniture, Fixtures & Equipment $42,000 - $95,000
Pre-Opening Costs $3,000 - $10,000
Leasehold Improvements $55,000 - $175,000
Signs & Installation $15,000 - $35,000
Opening Inventory $95,000 - $170,000
Grand Opening and Marketing $4,000 - $34,000
Accounts Receivable Financing $60,000 - $100,000
Computer and Pharmacy Equipment $26,000 - $40,000
Retail Solutions $0 - $14,075
Telepharmacy $0 - $35,865
Accreditation Costs $3,050 - $7,500
Additional Funds – 3 months $175,000 - $245,000
TOTAL $478,050 - $961,440

Medicine Shoppe

2023

Franchise Disclosure Document

Number of units

Training

The franchise agreement with Medicine Shoppe outlines several types of training and assistance that may be available to franchisees:

  1. Policies and Procedures Training
    Medicine Shoppe provides an initial manual containing operational policies and procedures. These may be supplemented through bulletins, the Internet, or other methods at the franchisor’s discretion. Franchisees are required to conform to these mandatory policies and correct any nonconformance within thirty days after receiving written notice.
  2. Transfer Training for New Franchisees
    If a franchise is transferred to a new owner, the transferee is required to attend training programs mandated by the franchisor. The company does not charge separately for this training.
  3. No Formal Training Program
    Despite the references to operational support, the franchise disclosure explicitly states that there is no formal training program for this franchise opportunity.

Territory Protection

Medicine Shoppe does not provide territory protection to its franchisees. The franchise agreement grants the right to operate a retail pharmacy at a single location, but this does not include exclusivity. Franchisees are not given any rights of first refusal or similar rights to acquire additional franchises, and any relocation of the business requires the franchisor’s consent.

In addition, franchisees may face direct competition from other franchisees, outlets operated by the franchisor, or other channels of distribution under either the same or different trademarks controlled by the franchisor.

The franchisor and its affiliates reserve the right to solicit and accept orders from any customers using any medium, including the internet, regardless of location. No compensation is provided to franchisees for business lost due to such competition.

Competitors

Below are some of

Medicine Shoppe

key competitors in the

Pharmacy

sector.

Franchise
Franchisees
Initial fee
Total investment
Revenue
Sign up
Gross Profit
Sign up
EBITDA
Sign up

297

New
+
-7%
-7%

n.a.

$478,000

$961,000

n.a.

$0

$xxx,xxx

n.a.

xx%

n.a.

n.a.

xx%

n.a.

Competitors

986 Pharmacy

986 Pharmacy is a retail pharmacy franchise offering prescriptions, specialty medications, and health services, serving community patients including Medicare and Medicaid beneficiaries, and known for personalized multilingual care, fast local delivery, and integrating independent pharmacy values with modern technology.

Franchisees

?

25
+
79%
79%
Investment

?

$280,000 - $671,000
Healthcare
Pharmacy

Pharmaconic

Pharmaconic is a pharmacy-ownership franchise offering full-service pharmacy operations, regulatory/licensing support and staffing, serving community-pharmacy owners and entrepreneurs, and known for fast-launch model, turnkey support and healthcare focus.

Franchisees

?

1
+
n.a.
n.a.
Investment

?

$302,000 - $415,000
Healthcare
Pharmacy

Medicap Pharmacy

Medicap Pharmacy provides personalized pharmaceutical services, ensuring patients receive expert guidance and care for their medication needs in a convenient and friendly environment.

Franchisees

?

67
+
-13%
-13%
Investment

?

$130,000 - $961,000
Healthcare
Pharmacy

Medicine Shoppe

Medicine Shoppe is a pharmacy franchise offering personalized pharmaceutical services, ensuring patients receive expert guidance and care for their medication needs.

Franchisees

?

297
+
-7%
-7%
Investment

?

$478,000 - $961,000
Healthcare
Pharmacy

Health Mart Pharmacy

Health Mart Pharmacy is a community pharmacy franchise offering personalized pharmaceutical care, prescriptions, and health services to local communities.

Franchisees

?

4657
+
-6%
-6%
Investment

?

$251,000 - $674,000
Healthcare
Pharmacy

Good Neighbor Pharmacy

Good Neighbor Pharmacy is a community pharmacy franchise that offers personalized healthcare services, prescriptions, and wellness support to patients.

Franchisees

?

2468
+
-2%
-2%
Investment

?

$279,000 - $575,000
Healthcare
Pharmacy

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