Medicine Shoppe Franchise FDD, Costs & Fees (2026)
Medicine Shoppe is a pharmacy franchise offering personalized pharmaceutical services, ensuring patients receive expert guidance and care for their medication needs.
KEY FRANCHISE STATS
Franchisees
?
297
+
-7%
-7%
Franchise fee
?
n.a.
Investment
?
$478,000 - $961,000
Revenue (AUV)
?
Undisclosed
$0
+
n.a.
n.a.
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Medicine Shoppehas empowered pharmacists to own and operate community-focused pharmacies. It was founded in 1970 in St. Louis, Missouri, and began franchising in 1971.
The company is still headquartered in St. Louis and operates under Medicine Shoppe International, a Cardinal Health company.
Medicine Shoppe franchise gives independent pharmacists the tools to deliver personalized care.
Franchisees offer prescription medications, over-the-counter health products, vitamins, wellness support, immunizations, and point-of-care testing. The franchise aims to restore the classic neighborhood pharmacy feel with modern efficiency.
Initial investment
The initial investment required for a Medicine Shoppe franchise is
$478,000 - $961,000.
That is the total cost you would need to finance if you were to start this franchise.
These costs are provided by the franchisor in the Franchise Disclosure Document.
Type of Expenditure
Amount
Initial Fee
$0
Furniture, Fixtures & Equipment
$42,000 - $95,000
Pre-Opening Costs
$3,000 - $10,000
Leasehold Improvements
$55,000 - $175,000
Signs & Installation
$15,000 - $35,000
Opening Inventory
$95,000 - $170,000
Grand Opening and Marketing
$4,000 - $34,000
Accounts Receivable Financing
$60,000 - $100,000
Computer and Pharmacy Equipment
$26,000 - $40,000
Retail Solutions
$0 - $14,075
Telepharmacy
$0 - $35,865
Accreditation Costs
$3,050 - $7,500
Additional Funds – 3 months
$175,000 - $245,000
TOTAL
$478,050 - $961,440
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Type of Expenditure
Amount
Initial Fee
$0
Furniture, Fixtures & Equipment
$42,000 - $95,000
Pre-Opening Costs
$3,000 - $10,000
Leasehold Improvements
$55,000 - $175,000
Signs & Installation
$15,000 - $35,000
Opening Inventory
$95,000 - $170,000
Grand Opening and Marketing
$4,000 - $34,000
Accounts Receivable Financing
$60,000 - $100,000
Computer and Pharmacy Equipment
$26,000 - $40,000
Retail Solutions
$0 - $14,075
Telepharmacy
$0 - $35,865
Accreditation Costs
$3,050 - $7,500
Additional Funds – 3 months
$175,000 - $245,000
TOTAL
$478,050 - $961,440
Franchise Disclosure Document
Below is Medicine Shoppe's 2023 Franchise Disclosure Document. Upgrade to Pro or purchase the FDD to view and download the document.
Number of units
Medicine Shoppe had 297 total units in 2023, of which 297 were franchised-owned and 0 company-owned.
Frequently Asked Questions
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Medicine Shoppe
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The franchise agreement with Medicine Shoppe outlines several types of training and assistance that may be available to franchisees:
Policies and Procedures Training Medicine Shoppe provides an initial manual containing operational policies and procedures. These may be supplemented through bulletins, the Internet, or other methods at the franchisor’s discretion. Franchisees are required to conform to these mandatory policies and correct any nonconformance within thirty days after receiving written notice.
Transfer Training for New Franchisees If a franchise is transferred to a new owner, the transferee is required to attend training programs mandated by the franchisor. The company does not charge separately for this training.
No Formal Training Program Despite the references to operational support, the franchise disclosure explicitly states that there is no formal training program for this franchise opportunity.
Territory Protection
Medicine Shoppe does not provide territory protection to its franchisees. The franchise agreement grants the right to operate a retail pharmacy at a single location, but this does not include exclusivity. Franchisees are not given any rights of first refusal or similar rights to acquire additional franchises, and any relocation of the business requires the franchisor’s consent.
In addition, franchisees may face direct competition from other franchisees, outlets operated by the franchisor, or other channels of distribution under either the same or different trademarks controlled by the franchisor.
The franchisor and its affiliates reserve the right to solicit and accept orders from any customers using any medium, including the internet, regardless of location. No compensation is provided to franchisees for business lost due to such competition.
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