Medical spa franchises operate at the intersection of aesthetics, wellness, and medical services, offering treatments such as IV hydration, injectables, laser therapy, and recovery services.
Capital requirements vary widely across the category, making payback efficiency and system scale critical factors when evaluating franchise performance.
Below are the top 5 medical spa franchises based on capital efficiency, network strength, and franchisee momentum.
Each franchise is evaluated using a balanced scoring model that weighs five core factors equally. The goal is to highlight brands that combine financial performance, operational maturity, and accessible investment levels. Scores are calculated as follows:
The final score out of 10 is calculated using this weighting model, ensuring the ranking highlights franchises that combine strong unit-level economics with system stability and consistent expansion.
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Prime IV Hydration & Wellness offers IV hydration therapy services, providing nutrient-infused solutions for hydration, wellness, and recovery support.

KEY FRANCHISE STATS
All you need to know about this franchise
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$539,000
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n.a.
What WE LIKE
Here's the rationale for our score
Prime IV provides IV therapy and wellness services in a retail medical spa setting.
Its top ranking is driven by strong system scale paired with solid franchisee growth.

Regenerative medicine clinic franchise providing non-surgical treatments for joint pain, utilizing innovative techniques like regenerative cell therapy and platelet-rich plasma (PRP) therapy.

KEY FRANCHISE STATS
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$467,000
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n.a.
What WE LIKE
Here's the rationale for our score
QC Kinetix focuses on regenerative medicine and non-surgical pain management.
Its ranking benefits from large system size and strong growth momentum.

The DripBar offers IV hydration therapy services, providing nutrient-infused solutions for hydration, energy, wellness, and recovery support.

KEY FRANCHISE STATS
All you need to know about this franchise
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$454,000
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n.a.
What WE LIKE
Here's the rationale for our score
The DRIPBaR delivers IV vitamin therapy in boutique spa environments.
Its ranking reflects a balance of system size and expansion velocity.

4Ever Young is a wellness franchise that takes a holistic approach to anti-aging, offering advanced treatments and therapies to help clients look and feel their best. Their services cater to a wide range of health and beauty needs.

KEY FRANCHISE STATS
All you need to know about this franchise
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$934,000
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n.a.
What WE LIKE
Here's the rationale for our score
4Ever Young offers anti-aging treatments including IV therapy, hormone replacement, and aesthetic services.
Its ranking is supported by strong growth despite higher capital requirements.

Live Hydration Spa offers IV hydration therapy services, providing nutrient-infused solutions for hydration and wellness support.

KEY FRANCHISE STATS
All you need to know about this franchise
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$404,000
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n.a.
What WE LIKE
Here's the rationale for our score
Live Hydration Spa specializes in IV therapy and wellness treatments.
Its ranking reflects balanced economics and steady system growth.